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Hardest Tissue in Human Body

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Hardest Part of Human Body: An Introduction

The human body gets its shape from the skeleton, which consists of bone and cartilage. Vital organs such as the lungs, heart, and brain are enclosed within the skeletal system. Enamel is the hardest substance in our body, but if we talk about which tissue is the hardest, it will be the Femoral and Temporal bone of the skull. Teeth and bone are the main substances in our body but the striking difference being teeth aren't actually bone though more than 99% of the calcium in our body is found in bones and teeth.

Sensitive Organ in Our Body

Our human body is made up of five sense organs- eyes, ears, nose, tongue and skin. An interesting fact is that there is a “sixth sense”, which is known as proprioception or the body's awareness of its place in space.

The skin is our body's most sensitive organ consisting of water, nutrients, lipids, and mineral deposits. The skin protects us from any kind of physical harm and, most importantly, reduces the harmful effects of UV radiation. The skin synchronises our body temperature. As most of our body is covered with skin, the most sensitive heat receptors are our elbows, nose and fingertips. The cold receptors are found on the chest, chin, nose, fingers, and upper lip. The skin covers 22 square feet of the surface area of a human body and is about 16% of total body weight.

Besides being a sensitive organ, it plays a vital role in providing immunity and protection against any kind of germs too. The skin, besides containing pain, and heat receptors, also contains hair follicles for the growth of hair. The skin, besides being the most sensitive, has varying degrees of thickness and thinness, for example, the skin below the eyes is the most sensitive, but it's thicker on the soles of feet and palms.

Weakest Part of Human Body

The human body comprises 206 bones which provide shape and form. The vital organs are also shielded by the bones, the femur being the longest, thickest and strongest, and the weakest and softest bone in our body is the clavicle which is the collar bone.

Interestingly the weak part of the body is dependent on the fact that what kind of force is operated on it, like the femur being the strongest bone, will handle impact before it cracks, but the ribs will break under much lesser impact of external force. If the impact is more than eyes, throat, knee joints, etc. will be considered weak depending on the force involved.

Hardest Cartilage of Body

Cartilage is a connective tissue found all over the body. It is a vital structural component and consists of chondrocyte cells mixed with collagen, thus, making it softer than bone. It provides support and structure to the tissue and cushions the joints. There are three types of cartilage found in our body, that are, Hyaline cartilage, Elastic cartilage, and Fibrocartilage.

  • Hyaline is found at the ends of joints, between the ribs and inside the nose.

  • Elastic is found in the external ear, epiglottis and larynx.

  • Fibrous is the hardest cartilage in intervertebral discs, joint capsules, and ligaments.

Fibrous cartilage is the strongest because of the presence of one after another layer of hyaline cartilage, matrix and layers of collagen fibres. It has strong resistance to ductile stresses and is tough and inflexible. It is found within the knee, in the intervertebral discs and in the pubic symphysis. Being the hardest cartilage, it forms the lining of the bony grooves of the tendon.

Interesting Fact

An interesting fact is that the thigh bone (Femur) is the strongest and longest bone in the human body and takes a lot of force to break it motor vehicle accidents are the major cause of femur fractures.

Important Questions

1. Which is the second hardest tissue in the body?

Ans. The dentin lies beneath enamel and cementum, it's harder than bone but softer than enamel. It being the second hardest tissue and possessing a softer texture than enamel, helps absorb the pressure from chewing. Dentine is denser than bone and has a yellowish colour seen through the tooth enamel Is the second hardest tissue.

2. What is the strongest bone in the human skull?

Ans. The mandible is the largest and strongest bone forming the face, the lower part of the jaw and major part of the mouth, as it holds the lower teeth in their position, assists in chewing food and is composed of the left and right halves of the lower jaw or mandible.

Key Features of Hardest Tissue of Human Body

  • The fibrocartilage is the strongest, specialised type in areas requiring tough support and strength.

  • The skin stores water and fats in its tissues providing insulation when needed.

  • Skin is the most sensitive and the largest organ of our body, the liver is the second largest.

  • The Mohs hardness scale is a qualitative ordinal scale. Tooth enamel ranks as hard as steel.

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FAQs on Hardest Tissue in Human Body

1. What is the hardest tissue in the human body?

The hardest tissue in the human body is tooth enamel. It is the highly mineralised, white, visible outer layer of our teeth. Its primary function is to protect the sensitive inner parts of the tooth, like dentin and pulp, from the daily wear and tear of chewing and from decay.

2. What makes tooth enamel so much harder than bone?

Tooth enamel's superior hardness is due to its composition. It consists of approximately 96% minerals, primarily in the form of hydroxyapatite crystals. In contrast, bone contains only about 70% minerals. The remaining 30% of bone is a flexible organic matrix, mostly collagen, which makes bone tough and resilient but less hard than the densely packed mineral structure of enamel.

3. What are the next hardest tissues in the body after enamel?

After tooth enamel, the next hardest tissues in the human body are:

  • Dentin: This tissue is found directly beneath the enamel and forms the main bulk of the tooth. It is harder than bone but softer and less brittle than enamel.
  • Bone: This connective tissue forms the body's skeleton. It provides structural support, protects vital organs, and is incredibly strong and resistant to compression.

4. What is the fundamental difference between a hard tissue and a soft tissue?

The key difference is mineralisation. Hard tissues, like bone and enamel, are mineralised, meaning their matrix is hardened with inorganic salts like calcium phosphate, which gives them rigidity and strength for support and protection. Soft tissues, such as muscles, ligaments, tendons, and skin, are non-mineralised. They are characterised by their flexibility, elasticity, and ability to connect or surround other body structures.

5. If enamel is the hardest tissue, why can teeth chip while bones can heal from a fracture?

This relates to the difference between hardness and toughness, and the presence of living cells. While enamel is harder (more resistant to scratching), it is also very brittle. Importantly, enamel contains no living cells, so it cannot regenerate or heal itself once damaged. Bone, on the other hand, is a living, dynamic tissue with a rich blood supply and cells (osteoblasts and osteoclasts) that continuously remodel and can heal fractures over time.

6. Is cartilage considered a hard tissue?

Cartilage is a unique type of firm connective tissue but is not typically classified as a hard tissue in the same way as bone. It lacks the extensive mineralisation that gives bone its rigidity. Instead, cartilage is known for its firm consistency and significant flexibility, acting as a cushion in joints (like the knee) and providing structural support in areas like the nose and ears.


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