Enantiomers
Enantiomers are a pair of molecules that exist in two forms that can not be superimposed on each other but are mirror images of each other.
Enantiomers have a Chiral Carbon. A Chiral Carbon is a center of Carbon that is bound to four distinct atoms or groups. The existence of Chiral Carbon is referred to as Chirality (in a molecule). Two molecules in each Chiral Carbon should have different configurations in order to become an Enantiomer. For Example, if a molecule has two Chiral Carbons and another molecule has two Chiral Carbons in the same molecular formula, the two molecules for both Chiral Carbons, not just one Chiral Carbon, should be different.
We discussed Enantiomer’s definition, now let’s study the Chirality and properties of Enantiomers.
It is also important to remember that more than one Chiral characteristic is possible for a molecule. These molecules have many geometric shapes that are considered to have (however, some of these forms may still be perfect mirror images of each other). It should also be noted that the physical and chemical properties of the two Enantiomers are almost identical when the Enantiomers are put in a symmetrical setting. They vary, however, in the directions in which polarised light is rotated by the plane. For instance, if one Enantiomer rotates the polarised light plane to the left, the other Enantiomer rotates the polarised light plane to the right.
Enantiomers are chemically similar in any other respect. A pair of Enantiomers is characterized by the direction in which polarised light is rotated. It can be dextrorotatory or laevorotatory, hence the term optical isomers are used. If two Enantiomers are similarly present, they are collectively referred to as a racemic mixture, a mixture that does not rotate polarized light because the other cancels the optical behavior of each Enantiomer.
Properties of Enantiomers
Enantiomers generally have identical physical properties such as melting point, boiling point, infrared absorptions, and NMR spectra.
It is important to realize that the melting point of one Enantiomer will be identical to that of the other Enantiomer, the melting point of a mixture of the two Enantiomers may be different.
This is because the intermolecular interactions between opposite Enantiomers that are between the R and S Enantiomers may be -different from those between Enantiomers that are between two molecules both of R or both of S stereoChemistry.
Structure of Enantiomers
As stereoisomers that are non-superimposable mirror images of one another, Enantiomers were introduced.
Any molecule which is not superimposed on its mirror image and thus exists is said to be Chiral and to show Chirality as a pair of Enantiomers. In comparison, any molecule which can be superimposed over its mirror image is a aChiral.
Indeed, it is possible to have two Enantiomers if a molecule contains a single atom that is tetrahedrally bound to four separate substituents.
It is important, however, that the four substituents differ from each other as if two of them were the same, then the structure would become superimposed on its mirror image and thus aChiral. It is better to refer to the atom linked to four distinct atoms as a stereogenic core or simply a stereocenter.
A commonly used alternate name for a stereocenter, although somewhat misleading, is located around the central atom, whereas Chirality is a property of the molecule as a whole that can not be located around one atom or a group of atoms.
Chemical Nature of Enantiomers
It is understood that chemical compounds exhibiting stereoisomerism and having different Enantiomeric structures frequently take part in chemical reactions with other Enantiomeric compounds. Currently, Enantiomers are considered to be certain biological molecules. In addition, it is important to remember that two different Enantiomers of the same chemical compound can affect many species in a completely different way. This phenomenon is commonly found in the effects on human beings of various medicines. In certain cases, only one of a drug's Enantiomers would be able to bring about the physiological improvements that are needed.
Did You Know?
Stereoisomers are Classified into diastereomers and Enantiomers. The difference between the two is given below.
Benefits of studying Enantiomers at Vedantu
Enantiomers is a very important topic that gets covered under Chemistry Class 12. In order to get familiar with the chapter, you should start with the basic topics and then reach for covering the complexities involved with the latter part of this chapter.
Experts at Vedantu have prepared detailed notes. After referring to the NCERT textbooks, students are advised to go through the explanation of this chapter in clear detail. This will help them to get familiarised with the topic.
In addition to the introduction of Enantiomers, the website of Vedantu provides brief details about Chiral Carbon. It is an essential part of the topic. Chiral Carbon is considered to be the subset of Enantiomers. You can find the standard answers for Chiral Carbon on both the app and the website.
While understanding the concept of Chiral molecules, you should also put your emphasis on learning the similarities and differences between the Chiral Carbon and the Enantiomers themselves.
After learning the introduction of Enantiomers, Vedantu focuses on the properties of these chemical molecules. Questions related to the properties form an important question in your Class 12 board Exams. The properties are explained in detail and simplified language.
Vedantu covers all the Class 12 Chemistry chapters from the NCERT textbook. NCERT books include clear pictures and structural representations related to the Enantiomers. For scoring well in your Exams, it is necessary that you support your answers with the relevant diagrams and structures of Enantiomers.
For the theoretical representation of the structural Enantiomers, Experts at Vedantu have covered the topic in 5 points. These points are kept short and to the point. Students will be able to understand the structure of Enantiomers in an easy manner.
Another important sub-concept that gets covered under the chapter is based on the chemical nature of Enantiomers. It is again, an important question that you should add to your list. In addition to the NCERT textbook, students can refer to the Vedantu website to revise the topic and clear their doubts.
The website also makes sure to contain small yet interactive ways to make the reader at ease. It will help you in grasping the given topics creatively. For Instance- At appropriate intervals, it poses questions to its students in the form of 'Did you know?'. It helps in keeping their minds engaged.
In this chapter, students often get a lot of questions related to the differentiation of two terms. While framing your answers, it's important that students use an appropriate tabular representation for the same. Vedantu has clearly described the difference between diastereomers and Enantiomers to help the students in scoring maximum for their Exams.
FAQs on What are Enantiomers?
1. What exactly are enantiomers in Chemistry?
Enantiomers are a pair of molecules that are non-superimposable mirror images of each other, much like your left and right hands. They are a specific type of stereoisomer. For a molecule to have an enantiomer, it must be chiral, which means it lacks an internal plane of symmetry.
2. How are enantiomers different from diastereomers?
The key difference is their mirror image relationship.
- Enantiomers are stereoisomers that are perfect, non-superimposable mirror images of each other.
- Diastereomers are stereoisomers that are not mirror images of each other. This happens in molecules that have two or more chiral centers.
3. Do enantiomers have the same physical and chemical properties?
Enantiomers share identical physical properties like melting point, boiling point, and density. Their chemical properties are also the same, with two key exceptions: their interaction with plane-polarised light and their reactions with other chiral molecules.
4. What does it mean for enantiomers to be optically active?
Optical activity is the unique ability of chiral molecules to rotate the plane of polarised light. One enantiomer of a pair will rotate the light in a clockwise direction (+), while its mirror image counterpart will rotate it by the exact same amount in a counter-clockwise direction (–). This is one of the few properties that can be used to tell them apart.
5. What are some simple examples of enantiomers?
A classic example is the amino acid Alanine, which exists as L-Alanine and D-Alanine. Another common one is Lactic acid, found in sour milk, which has (+)-Lactic acid and (-)-Lactic acid forms. In medicine, the drug Ibuprofen is a good example, where only one enantiomer (S-Ibuprofen) is responsible for its pain-relieving effects.
6. What is the difference between a chiral carbon and an enantiomer?
A chiral carbon is a feature within a single molecule—it is a carbon atom bonded to four different groups. The presence of a chiral carbon is often what makes a molecule chiral. In contrast, the term enantiomer is used to describe the relationship between two separate molecules that are non-superimposable mirror images of each other. So, a chiral carbon is a part of a molecule, while an enantiomer is a related but separate molecule.
7. How is the R/S system used to name different enantiomers?
The R/S system provides a clear and unique name for each enantiomer. It works by assigning priorities to the four groups attached to the chiral center based on atomic number.
- If tracing the priorities from highest to lowest (1 to 3) goes in a clockwise direction, the configuration is named R (from the Latin *Rectus*, for right).
- If the direction is counter-clockwise, it is named S (from the Latin *Sinister*, for left).
8. Why are enantiomers so important in biology and medicine?
Our bodies are built with chiral molecules like amino acids and sugars. Receptors and enzymes in our cells are also chiral, so they can distinguish between the two enantiomers of a substance. This is called biological specificity. For a drug, one enantiomer might fit a receptor perfectly and provide a therapeutic benefit, while its mirror image might not fit, or worse, it could fit a different receptor and cause harmful side effects.
